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As featured in A*STAR newsroom and Genetic Engineering and Biotechnology News. A new spinoff company is about to launch a computer model that aims to accelerate process development by speeding up the optimization of cell culture media. AuctuCel, which plans to open for business on June 1, will offer a mechanistic model that requires less client data to work than those based on artificial intelligence (AI), according to Zach Pang, PhD, group leader at the A*STAR Bioprocessing Technology Institute in Singapore. Pang, who helped develop the model and introduced it at Bioprocessing Summit Europe in March, said, “Our key message is that you no longer have to perform laborious, time-consuming, manual optimization for culture media. Our new computational approach gives you an option that’s much faster and cheaper, helping accelerate your entire development timeline.” Pang explained that the team’s deep knowledge of culture media helped them to develop a mechanistic model, which doesn’t require large training datasets to work. “It doesn’t merely rely on correlation or a statistical method,” he added. “The person who runs our model is a hard-core biologist who’s taken up mechanistic modeling as, for any mechanistical model, you need to know what’s going on.”
